Compound name
BI-1374
Protein family
Protein Kinase
Target name
CDK8
Affinity biochemical (nM)
671
CG-Set
Kinase set
Recommended Concentration
100 nM
Compound EUbOPEN ID
EUB0000163b
SMILES
CN(C)C(=O)Cn1cc(-c2ccc(-c3nnc4ccccn34)cc2)cn1
InChIKey
ODRITQGYYWHQGM-INIZCTEOSA-N
NCBI gene ID
1024
UniProt ID
P49336
Synonyms
K35
Mode of action
Negative control for BI-1347
Affinity biochemical definition
IC50
Affinity biochemical assay type
Lantha screen (CDK8/cyclinC inhibition)
Affinity Biochemical Source Knowledge
https://opnme.com/molecules/cdk8-bi-1347
Affinity biochemical relation
=