Compound name
SGC-CAMKK2-1 (UNC-YL-36)
Protein family
Protein Kinase
Target name
CAMKK2
Affinity biochemical (nM)
30
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0000167b
SMILES
Cc1cccc(-c2cnc3occ(-c4ccc(C(=O)O)c(C5CCCC5)c4)c3c2)c1
InChIKey
TXIYVFVMXNFNRX-UHFFFAOYSA-N
NCBI gene ID
10645
UniProt ID
Q96RR4
Synonyms
CAMKK, KIAA0787, CAMKKB, MGC15254
Mode of action
Inhibitor
Negative control
SGC-CAMKK2-1N (UNC-YL-83)
Affinity biochemical definition
IC50
Affinity biochemical assay type
Enzymatic activity assay
Affinity Biochemical Source Knowledge
https://www.thesgc.org/chemical-probes/SGC-CAMKK2-1
Affinity biochemical relation
=
Selectivity platform
KinomeScan (DiscoverX)
Selectivity platform number of targets
403
Selectivity remarks
Screened at 1 µM, off-target PoC of 12%
Selectivity Source Knowledge
https://www.thesgc.org/chemical-probes/SGC-CAMKK2-1
Selectivity Number of Off-targets
1