Compound name
GSK-J4
Protein family
KDM
Target name
KDM6A/UTX@Demethylase
Affinity biochemical (nM)
6600
CG-Set
Other targets
Recommended Concentration
100 nM
Compound EUbOPEN ID
EUB0000217b
SMILES
CCOC(=O)CCNc1cc(N2CCc3ccccc3CC2)nc(-c2ccccn2)n1
InChIKey
WBKCKEHGXNWYMO-UHFFFAOYSA-N
NCBI gene ID
7403
UniProt ID
O15550
Mode of action
Pro-drug of GSK-J1
Negative control
GSK-J5
Affinity biochemical definition
IC50
Affinity biochemical assay type
AlphaLISA based assay
Affinity Biochemical Source Knowledge
https://doi.org/10.1038/nature13688
Affinity biochemical relation
=