Compound name
CP-96345
Protein family
GPCR
Target name
TACR1
Affinity biochemical (nM)
1.48
Affinity on-target cellular (nM)
0.79
Compound EUbOPEN ID
EUB0000363a
SMILES
COC1=CC=CC=C1CN[C@H]1C2CCN(CC2)[C@H]1C(C1=CC=CC=C1)C1=CC=CC=C1
InChIKey
FLNYLINBEZROPL-NSOVKSMOSA-N
NCBI gene ID
6869
UniProt ID
P25103
Synonyms
SPR, NK1R, NKIR
Mode of action
Antagonist
Affinity biochemical definition
Ki
Affinity biochemical assay type
Binding affinity towards Tachykinin receptor 1 expressed in CHO cells using [3H][Pro9]-SP as radioligand
Affinity Biochemical Source Knowledge
11266164
Affinity biochemical relation
=
Affinity on-target cellular definition
Kd
Affinity on-target cellular assay type
Antagonist activity against Tachykinin receptor 1 in dog isolated carotid artery
Affinity on-target cellular relation
=