Compound name
IBUTAMOREN
Protein family
GPCR
Target name
GHSR
Affinity biochemical (nM)
0.57
Affinity on-target cellular (nM)
1.31
Compound EUbOPEN ID
EUB0000425aMSA
SMILES
O=C(N1CCC2(C(C=CC=C3)=C3N(S(C)(=O)=O)C2)CC1)[C@H](NC(C(C)(N)C)=O)COCC4=CC=CC=C4.OS(=O)(C)=O
InChIKey
DUGMCDWNXXFHDE-VZYDHVRKSA-N
NCBI gene ID
2693
UniProt ID
Q92847
Mode of action
Agonist
Affinity biochemical definition
IC50
Affinity biochemical assay type
Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor
Affinity Biochemical Source Knowledge
10636230
Affinity biochemical relation
=
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a
Affinity on-target cellular relation
=