Compound name
ESTRADIOL
Protein family
GPCR
Target name
GPER1
Affinity biochemical (nM)
3.94
Affinity on-target cellular (nM)
0.3
CG-Set
Not included in the set
Compound EUbOPEN ID
EUB0000449a
SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
InChIKey
VOXZDWNPVJITMN-ZBRFXRBCSA-N
NCBI gene ID
2852
UniProt ID
Q99527
Synonyms
FEG-1, GPCR-Br, LERGU, LERGU2, DRY12, LyGPR, CEPR
Mode of action
Agonist
Affinity biochemical definition
Ki
Affinity biochemical assay type
Inhibition of estrogen binding to GPR30 (unknown origin)
Affinity Biochemical Source Knowledge
23672690
Affinity biochemical relation
=
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
Agonist activity at GPR30 (unknown origin) by calcium mobilization assay
Affinity on-target cellular relation
=