Compound name
BAY 60-6583
Protein family
GPCR
Target name
ADORA2B
Affinity on-target cellular (nM)
30.9
Compound EUbOPEN ID
EUB0000460a
SMILES
NC(=O)CSC1=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C(C#N)C(N)=N1
InChIKey
ZTYHZMAZUWOXNC-UHFFFAOYSA-N
NCBI gene ID
136
UniProt ID
P29275
Mode of action
Agonist
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
Agonist activity at human adenosine A2B receptor expressed in CHO cell membranes assessed as induction of cAMP accumulation by AlphaScreen assay
Affinity on-target cellular relation
=