Compound name
LPA2 Antagonist 1
Protein family
GPCR
Target name
LPAR2
Affinity on-target cellular (nM)
16.98
Compound EUbOPEN ID
EUB0000464a
SMILES
C[C@@H](CN1CCN(CC1)S(=O)(=O)C1=CC=C(Cl)C(Cl)=C1)NC1=C2SC=C(C)C2=NC=N1
InChIKey
BPRNMVDTWIHULJ-AWEZNQCLSA-N
NCBI gene ID
9170
UniProt ID
Q9HBW0
Synonyms
EDG-4, LPA2
Mode of action
Antagonist
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assay
Affinity on-target cellular relation
=