Compound name
AC 264613
Protein family
GPCR
Target name
F2RL1
Affinity biochemical (nM)
30.2
Affinity on-target cellular (nM)
30.9
Compound EUbOPEN ID
EUB0000469a
SMILES
C\C(=N/NC(=O)[C@H]1[C@@H](CNC1=O)C1=CC=CC=C1)C1=CC=CC(Br)=C1
InChIKey
RQKXQCSEZPQBNZ-QSBCOWLBSA-N
NCBI gene ID
2150
UniProt ID
P55085
Synonyms
PAR2
Mode of action
Agonist
Affinity biochemical definition
EC50
Affinity biochemical assay type
Agonist activity at human PAR2 expressed in HEK293T cells assessed as stimulation of phosphatidylinositol hydrolysis after 45 mins by scintillation counting analysis
Affinity Biochemical Source Knowledge
23895492
Affinity biochemical relation
=
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assay
Affinity on-target cellular relation
=