Compound name
LATREPIRDINE
Protein family
GPCR
Target name
HRH1
Affinity on-target cellular (nM)
158.49
CG-Set
Not included in the set
Compound EUbOPEN ID
EUB0000480a
SMILES
CN1CCC2=C(C1)C1=CC(C)=CC=C1N2CCC1=CC=C(C)N=C1
InChIKey
JNODQFNWMXFMEV-UHFFFAOYSA-N
NCBI gene ID
3269
UniProt ID
P35367
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium level increase during phase-1 compound incubated before histamine addition by Fura-2 based fluorometric assay
Affinity on-target cellular relation
=