Compound name
WZ4003
Protein family
Protein Kinase
Target name
NUAK1
Affinity biochemical (nM)
20
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0000627a
SMILES
CN1CCN(C2=CC=C(NC3=NC=C(Cl)C(OC4=CC=CC(NC(CC)=O)=C4)=N3)C(OC)=C2)CC1
InChIKey
SDGJBAUIGHSMRI-UHFFFAOYSA-N
NCBI gene ID
9891
UniProt ID
O60285
Synonyms
ARK5, KIAA0537
Mode of action
Inhibitor
Affinity biochemical definition
IC50
Affinity biochemical assay type
Radiometric kinase assay
Affinity Biochemical Source Knowledge
https://doi.org/10.1042/BJ20131152
Affinity biochemical relation
=
Selectivity platform
Kinase panel (international centre for protein kinase profiling)
Selectivity platform number of targets
140
Selectivity remarks
Screened at1 µM, closest targets as % of kinase activity.: STK33 (33%), ULK2 (37%)
Selectivity Source Knowledge
https://doi.org/10.1042/BJ20131152
Selectivity Number of Off-targets
0