EUB0000656a_PIK3CG

Chemical structure of compound EUB0000656a
Compound name
ZSTK474
Protein family
Protein Kinase
Target name
PIK3CG
Affinity biochemical (nM)
49
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0000656a
SMILES
FC(F)C1=NC(C=CC=C2)=C2N1C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3
InChIKey
HGVNLRPZOWWDKD-UHFFFAOYSA-N
NCBI gene ID
5294
UniProt ID
P48736
Mode of action
Inhibitor
Affinity biochemical definition
IC50
Affinity biochemical assay type
HTRF-based inhibition assay
Affinity Biochemical Source Knowledge
https://doi.org/10.1038/aps.2010.150
Affinity biochemical relation
=
Selectivity platform
Kinase panel, literature
Selectivity platform number of targets
139
Selectivity remarks
Screened at 30 µM, highly specific
Selectivity Source Knowledge
https://doi.org/10.1093/jnci/djj133
Selectivity Number of Off-targets
0