Compound name
GSK923295
Protein family
Kinesin
Target name
CENPE
Affinity biochemical (nM)
2.2
CG-Set
Other targets
Recommended Concentration
100 nM
Compound EUbOPEN ID
EUB0000734a
SMILES
O=C(C1=CC=C(OC(C)C)C(Cl)=C1)N[C@H](CNC(CN(C)C)=O)CC2=CC=C(C3=CN(C=CC=C4[C@H](C)O)C4=N3)C=C2
InChIKey
WHMXDBPHBVLYRC-OFVILXPXSA-N
NCBI gene ID
1062
UniProt ID
Q02224
Synonyms
CENP-E, KIF10, MCPH13, PPP1R61
Mode of action
Allosteric inhibitor
Affinity biochemical definition
Ki
Affinity biochemical assay type
Enzyme inhibition assay
Affinity Biochemical Source Knowledge
https://pubmed.ncbi.nlm.nih.gov/20167803/
Affinity biochemical relation
=