Compound name
MSC2705360A
Protein family
Protein Kinase
Target name
SRPK3
Affinity biochemical (nM)
3500
Affinity on-target cellular (nM)
9962
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001046a
SMILES
Clc4cc1c([nH]c(c1)-c2nc(ccn2)NCc3c(nccc3)N(S(=O)(=O)C)C)cc4
InChIKey
MXAVRMOXZMBKGE-UHFFFAOYSA-N
NCBI gene ID
26576
UniProt ID
Q9UPE1
Synonyms
MSSK1
Mode of action
Negative control for MSC2711186A
Affinity biochemical definition
IC50
Affinity biochemical assay type
Biochemical activity assay (Reaction Biology)
Affinity Biochemical Source Knowledge
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c01705
Affinity biochemical relation
=
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
NanoBRET assay (in HEK293T cells, lysed mode)
Affinity on-target cellular source knowledge
https://pubs.acs.org/doi/full/10.1021/acs.jmedchem.2c01705
Affinity on-target cellular relation
=