Compound name
PFI-7
Target name
GID4
Affinity biochemical (nM)
80
Affinity on-target cellular (nM)
600
CG-Set
Other targets set
Recommended Concentration
100 nM
Compound EUbOPEN ID
EUB0001127a
SMILES
C1C[C@H](CC[C@H]1c1nc2ccccc2[nH]1)NC(CNCc1cc2ccccc2[nH]1)=O
InChIKey
HLHNFJNSQZZUNW-MAEOIBBWSA-N
NCBI gene ID
79018
UniProt ID
Q8IVV7
Synonyms
C17orf39, VID2, VID24
Mode of action
Inhibitor
Negative control
PFI-7N
Affinity biochemical definition
Kd
Affinity biochemical assay type
SPR measurement
Affinity Biochemical Source Knowledge
https://www.thesgc.org/chemical-probes/PFI-7
Affinity biochemical relation
0
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
NanoBRET assay (interaction between NanoLuc® tagged degrons and full-length GID4)
Affinity on-target cellular source knowledge
https://www.thesgc.org/chemical-probes/PFI-7
Affinity on-target cellular relation
0