Compound name
GSK943
Protein family
Bromodomain
Target name
BRDT@BD2
CG-Set
Epigenetic set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001134a
SMILES
CNC(=O)c1cc(C(=O)N[C@@H]2[C@H]3COC[C@H]32)cc2c1O[C@@H](CF)[C@@H]2c1ccccc1
InChIKey
WZQLVEPIBAOOGF-PXTPFGJHSA-N
NCBI gene ID
676
UniProt ID
Q58F21
Synonyms
BRD6, CT9
Mode of action
Negative control for GSK973
Selectivity platform
GPCR panel (PDSP screen)
Selectivity platform number of targets
45
Selectivity remarks
Screened at 10 µM, in-vitro potency of closest target: Ki(GABA/BZP) = 473.91 nM
Selectivity Source Knowledge
https://www.sgc-ffm.uni-frankfurt.de/chemProbes#!specificprobeoverview/GSK973
Selectivity Number of Off-targets
0