Compound name
GSK0660
Protein family
NR
Target name
PPARD
Affinity on-target cellular (nM)
5500
CG-Set
NR
Recommended Concentration
10 µM
Compound EUbOPEN ID
EUB0001150a
SMILES
O=S(NC(C=C1)=C(OC)C=C1NC2=CC=CC=C2)(C3=C(C(OC)=O)SC=C3)=O
InChIKey
NDFKBGWLUHKMFY-UHFFFAOYSA-N
NCBI gene ID
5467
UniProt ID
Q03181
Synonyms
NUC1, NUCII, FAAR, NR1C2
Mode of action
Antagonist
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
cell-based
Affinity on-target cellular source knowledge
https://doi.org/10.1210/me.2007-0190
Affinity on-target cellular relation
=
Selectivity platform
Reportergenassay
Selectivity platform number of targets
26
Selectivity remarks
inactive at 1 µM for UL48, RXRA, HNF4A, NR2C1, NR2E1, NR4A1, NR5A1
Selectivity Source Knowledge
https://zenodo.org/records/10474037