Compound name
SR 1001
Protein family
NR
Target name
RORA
Affinity on-target cellular (nM)
900
CG-Set
NR
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001158a
SMILES
CC(NC1=NC(C)=C(S(NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)(=O)=O)S1)=O
InChIKey
OZBSSKGBKHOLGA-UHFFFAOYSA-N
NCBI gene ID
6095
UniProt ID
P35398
Synonyms
RZRA, ROR1, ROR2, ROR3, NR1F1
Mode of action
Inverse Agonist
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
cell-based
Affinity on-target cellular source knowledge
https://zenodo.org/records/10474037
Affinity on-target cellular relation
=
Selectivity platform
Reportergenassay
Selectivity platform number of targets
26
Selectivity remarks
inactive at 1 µM for UL48, RXRA, HNF4A, NR2C1, NR2E1, NR4A1, NR5A1
Selectivity Source Knowledge
https://zenodo.org/records/10474037