Compound name
DG-172
Protein family
NR
Target name
PPARD
Affinity on-target cellular (nM)
1800
CG-Set
NR
Recommended Concentration
10 µM
Compound EUbOPEN ID
EUB0001483aCl
SMILES
CN1CCN(CC1)C2=CC=C(C=C2)C=C(C#N)C3=CC=CC=C3Br
InChIKey
SABUORLIDVBCPI-WTLOABTRSA-N
NCBI gene ID
5467
UniProt ID
Q03181
Synonyms
NUC1, NUCII, FAAR, NR1C2
Mode of action
Antagonist
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
cell-based
Affinity on-target cellular source knowledge
https://doi.org/10.1021/jm2017122
https://zenodo.org/records/10474037
Affinity on-target cellular relation
=
Selectivity platform
Reportergenassay
Selectivity platform number of targets
26
Selectivity remarks
inactive at 10 µM for UL48, RXRA, HNF4A, NR2C1, NR2E1, NR4A1, NR5A1
Selectivity Source Knowledge
https://zenodo.org/records/10474037