Compound name
GNE-6689
Protein family
Protein Kinase
Target name
IRAK4
Affinity on-target cellular (nM)
9500
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001559a
SMILES
CN(C(=O)c1cnn2cccnc12)c1cc2c(cc1N1CCOCC1)C(=O)N(C[C@@H](F)C(C)(C)O)C2
InChIKey
JREVKKCSBRLATM-OAQYLSRUSA-N
NCBI gene ID
51135
UniProt ID
Q9NWZ3
Synonyms
NY-REN-64
Mode of action
Negative control for GNE-2256
Affinity on-target cellular definition
EC50
Affinity on-target cellular assay type
NanoBRET assay (HEK293T cells)
Affinity on-target cellular source knowledge
https://www.sgc-ffm.uni-frankfurt.de/chemProbes#!specificprobeoverview/GNE-2256
Affinity on-target cellular relation
=