Compound name
RL2578
Protein family
Protein Kinase
Target name
AKT1
Affinity biochemical (nM)
920
Affinity on-target cellular (nM)
1900
CG-Set
Kinase set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001563a
SMILES
C=CC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(-c5ccc6c(c5)NC(=O)CO6)cc4)CC3)c2c1
InChIKey
DHRJWFCFMBINAK-UHFFFAOYSA-N
NCBI gene ID
207
UniProt ID
P31749
Synonyms
RAC, PKB, PRKBA, AKT, RAC-alpha
Mode of action
Negative control for Borussertib
Affinity biochemical definition
IC50
Affinity biochemical assay type
HTFR assay
Affinity Biochemical Source Knowledge
https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/Borussertib
Affinity biochemical relation
=
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
NanoBRET assay (in HEK293T cells)
Affinity on-target cellular source knowledge
https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/Borussertib
Affinity on-target cellular relation
=