Compound name
BI01372674
Protein family
SLC
Target name
SLC13A5
Affinity on-target cellular (nM)
100000
CG-Set
Ion Channel
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001695a
SMILES
CP(C)(=O)c1ccc(CNC(=O)C2CCN(S(=O)(=O)c3cc(Cl)cc(Cl)c3)CC2)cc1
InChIKey
GSNNWZZIEKEEQF-UHFFFAOYSA-N
NCBI gene ID
284111
UniProt ID
Q86YT5
Synonyms
EIEE25 INDY NACT mIndy
Mode of action
Negative control for BI01383298
Affinity on-target cellular definition
IC50
Affinity on-target cellular assay type
SLC13A5 citrate uptake assay (using HEK293 cells)
Affinity on-target cellular source knowledge
https://www.opnme.com/molecules/slc13a5-bi01383298
Affinity on-target cellular relation
>
Selectivity platform
SafetyScreen44™ (Eurofins)
Selectivity platform number of targets
44
Selectivity remarks
Screened at 10 µM against a panel of ion channels, GPCRs, hydrolases, and other enzymes, closest target as % of contr.: COX-2 (80%), full screening data available on OpenMe website, https://www.opnme.com/molecules/slc13a5-bi01383298;
Selectivity Source Knowledge
https://www.opnme.com/molecules/slc13a5-bi01383298
Selectivity Number of Off-targets
0