Compound name
BI-2051
Protein family
Hydrolase
Target name
DPAP1
Affinity biochemical (nM)
0.3
CG-Set
Other targets set
Recommended Concentration
100 nM
Compound EUbOPEN ID
EUB0001716a
SMILES
N#Cc1ccc(C#CC[C@@H](C#N)NC(=O)[C@@H]2CCCCN2)cc1F
InChIKey
XFLXOPFMUQXKTL-RDJZCZTQSA-N
Mode of action
Inhibitor
Negative control
BI-2054
Affinity biochemical definition
IC50
Affinity biochemical assay type
Enzymatic assay
Affinity Biochemical Source Knowledge
https://www.opnme.com/molecules/dpap1-inhibitor-bi-2051
Affinity biochemical relation
=
Selectivity platform
SafetyScreen44™ (Eurofins)
Selectivity platform number of targets
44
Selectivity remarks
Screened at 10 µM against 121 GPCRs, ion channels, and kinases, closest target as % of control: KAPPA(KOP, 73%), full screening data available on OpenMe website, https://www.opnme.com/molecules/dpap1-inhibitor-bi-2051;
Selectivity Source Knowledge
https://www.opnme.com/molecules/dpap1-inhibitor-bi-2051
Selectivity Number of Off-targets
0