Compound name
BI-9313
Protein family
Lipid Transfer Protein
Target name
CETP
Affinity biochemical (nM)
2794
CG-Set
Other targets set
Recommended Concentration
1 µM
Compound EUbOPEN ID
EUB0001758a
SMILES
CC(C)c1nc2c(c3c1[C@H](c1ccc(C(F)(F)F)cc1)OC31CCOCC1)[C@H](O)CC(C)(C)C2
InChIKey
HKASDKLLEVWKJA-DVECYGJZSA-N
NCBI gene ID
1071
UniProt ID
P11597
Synonyms
BPIFF, HDLCQ10
Mode of action
Negative control for BI-5756
Affinity biochemical definition
IC50
Affinity biochemical assay type
TransF assay (transfer inhibition of a fluorescence labelled lipid from donor vesicles to LDL)
Affinity Biochemical Source Knowledge
https://www.opnme.com/molecules/cetp-inhibitor-bi-5756
Affinity biochemical relation
=
Selectivity platform
SafetyScreen44™ (Eurofins)
Selectivity platform number of targets
44
Selectivity remarks
Screened at 10 µM against a panel of GPCRs, ion channels, and other enzymes, closest target as % of control: PDE4D2 (29%), full screening data available on OpenMe website, https://www.opnme.com/molecules/cetp-inhibitor-bi-5756;
Selectivity Source Knowledge
https://www.opnme.com/molecules/cetp-inhibitor-bi-5756
Selectivity Number of Off-targets
0