Compound name
C3TD879 NC
Protein family
Protein Kinase
Target name
CIT
Affinity biochemical (nM)
30000
Affinity on-target cellular (nM)
10000
CG-Set
Kinase set
Recommended Concentration
2 µM
Compound EUbOPEN ID
EUB0003025a
SMILES
Cc1cc(ccc1c1cncc2c1cc(C)[nH]2)NC([C@@H](CC(C)(C)C)N)=O
InChIKey
HHXRZSZBSWPCKL-LJQANCHMSA-N
NCBI gene ID
11113
UniProt ID
O14578
Synonyms
KIAA0949, STK21, CRIK, CITK
Mode of action
Negative control for C3TD879
Affinity biochemical definition
IC50
Affinity biochemical assay type
LANCE TR-FRET assay (using 10 µM ATP)
Affinity Biochemical Source Knowledge
https://pubmed.ncbi.nlm.nih.gov/38330278/
Affinity biochemical relation
>
Affinity on-target cellular definition
Kd
Affinity on-target cellular assay type
NanoBRET Assay (HEK293T cells)
Affinity on-target cellular source knowledge
https://pubmed.ncbi.nlm.nih.gov/38330278/
Affinity on-target cellular relation
>