1. Chemogenomics
2. ADORA2B

ADORA2B

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

136

264

P29275

AA2BR_HUMAN

adenosine A2b receptor

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000458a

GS 6201

CCCN1C(=O)N(CC)C2=C(NC(=N2)C2=CN(CC3=CC=CC(=C3)C(F)(F)F)N=C2)C1=O

KOYXXLLNCXWUNF-UHFFFAOYSA-N

Antagonist

ADORA2B

Yes

Yes

Yes

Yes

EUB0000460a

BAY 60-6583

NC(=O)CSC1=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C(C#N)C(N)=N1

ZTYHZMAZUWOXNC-UHFFFAOYSA-N

Agonist

ADORA2B

Yes

Yes

No

Yes