1. Chemogenomics
  2. AURKB

AURKB

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
9212
11390
Q96GD4
AURKB_HUMAN
Aurora kinase B
Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000146b
TP-0903
Chemical structure of compound TP-0903
CN1CCN(Cc2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)N(C)C)n3)cc2)CC1
YUAALFPUEOYPNX-UHFFFAOYSA-N
AURKA
,
AURKB
,
AXL
Yes
Yes
Yes
No
EUB0000659a
ZM-447439
Chemical structure of compound ZM-447439
COC1=C(C=C(N=CN=C2NC3=CC=C(NC(C4=CC=CC=C4)=O)C=C3)C2=C1)OCCCN5CCOCC5
OGNYUTNQZVRGMN-UHFFFAOYSA-N
AURKB
Yes
Yes
No
No
EUB0000663a
Barasertib-HQPA
Chemical structure of compound Barasertib-HQPA
CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO
QYZOGCMHVIGURT-UHFFFAOYSA-N
AURKB
Yes
Yes
No
No
EUB0000674a
GSK1070916
Chemical structure of compound GSK1070916
CN(C)CC1=CC=CC(C2=CC3=C(C4=CN(CC)N=C4C5=CC=C(NC(N(C)C)=O)C=C5)C=CN=C3N2)=C1
QTBWCSQGBMPECM-UHFFFAOYSA-N
AURKB
,
AURKC
Yes
Yes
No
No