1. Chemogenomics
2. BRD1@BRD

BRD1@BRD

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

23774

1102

O95696

BRD1_HUMAN

bromodomain containing 1

Bromodomain

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000205c

NI-57

COc1cc(C#N)ccc1S(=O)(=O)Nc1ccc2c(c1)cc(C)c(=O)n2C

UEMQPCYDWCSVCU-UHFFFAOYSA-N

inhibitor

BRD1@BRD

,

BRPF1@BRD

,

BRPF3@BRD

Yes

Yes

No

Yes

EUB0000224e

PFI-4

COc1ccccc1C(O)=Nc1cc2c(cc1N1CCCC1)n(C)c(=O)n2C

QCIJLRJBZDBVDB-UHFFFAOYSA-N

BRD1@BRD

,

BRPF1@BRD

,

BRPF3@BRD

Yes

Yes

No

No

EUB0000323b

OF-1

COC1=CC(N2C)=C(C=C1NS(=O)(C3=CC=C(C=C3C)Br)=O)N(C)C2=O

YUNQZQREIHWDQT-UHFFFAOYSA-N

BRD1@BRD

,

BRPF1@BRD

,

BRPF3@BRD

Yes

Yes

No

No