1. Chemogenomics
2. EP300@Acetyltransferase

EP300@Acetyltransferase

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

2033

3373

Q09472

EP300_HUMAN

E1A binding protein p300

HAT

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000326a

A-486

C[C@H](N(C(CN1C([C@]2(OC1=O)CCC3=C2C=C(NC(NC)=O)C=C3)=O)=O)CC4=CC=C(F)C=C4)C(F)(F)F

MTTJOZOOUCZVHO-BSEYFRJRSA-N

Neg Ctrl (A-485)

CREBBP@Acetyltransferase

,

EP300@Acetyltransferase

Yes

Yes

No

Yes

EUB0000328a

A-485

C[C@H](N(C(CN1C([C@]2(OC1=O)CCC3=CC(NC(NC)=O)=CC=C23)=O)=O)CC4=CC=C(F)C=C4)C(F)(F)F

VRVJKILQRBSEAG-BSEYFRJRSA-N

HAT domain

CREBBP@Acetyltransferase

,

EP300@Acetyltransferase

Yes

Yes

No

Yes