1. Chemogenomics
2. ESR2

ESR2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

2100

3468

Q92731

ESR2_HUMAN

estrogen receptor beta

Nuclear receptor

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000556a

WAY200070

C1=CC(=CC=C1C2=NC3=C(O2)C(=CC(=C3)O)Br)O

BAAILVWEAXFTSF-UHFFFAOYSA-N

ESR2

Yes

Yes

No

Yes

EUB0000557a

diarylpropionitrile

C1=CC(=CC=C1CC(C#N)C2=CC=C(C=C2)O)O

GHZHWDWADLAOIQ-UHFFFAOYSA-N

ESR1

,

ESR2

Yes

Yes

No

Yes

EUB0000580a

ethinylestradiol

C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O

BFPYWIDHMRZLRN-SLHNCBLASA-N

ESR1

,

ESR2

Yes

Yes

No

Yes

EUB0000584a

bazedoxifene

CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O

UCJGJABZCDBEDK-UHFFFAOYSA-N

ESR1

,

ESR2

Yes

Yes

Yes

Yes