1. Chemogenomics
2. GPR35

GPR35

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

2859

4492

Q9HC97

GPR35_HUMAN

G protein-coupled receptor 35

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000484aNa

Pamoic acid

OC(=O)C1=CC2=CC=CC=C2C(CC2=C3C=CC=CC3=CC(C(O)=O)=C2O)=C1O

YGLLICRFEVEWOZ-UHFFFAOYSA-L

Agonist

GPR35

Yes

Yes

No

Yes

EUB0000504a

TC-G 1001

OC(=O)C1=CC=C(\C=C2/SC(NC3=CC=CC=C3F)=NC2=O)C=C1

SYCKPHBALHXMIR-ZROIWOOFSA-N

Agonist

GPR35

Yes

Yes

No

Yes

EUB0000871b

ML-145

C\C(\C=C1/SC(=S)N(CCCC(=O)NC2=CC(O)=C(C=C2)C(O)=O)C1=O)=C/C1=CC=CC=C1

COFMYJWNXSFLKQ-QIROLCGISA-N

Antagonist

GPR35

Yes

Yes

Yes

Yes