1. Chemogenomics
2. GRM8

GRM8

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

2918

4600

O00222

GRM8_HUMAN

glutamate metabotropic receptor 8

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000356a

DL-AP4

NC(CCP(O)(O)=O)C(O)=O

DDOQBQRIEWHWBT-UHFFFAOYSA-N

Agonist

GRM8

Yes

Yes

No

Yes

EUB0000429a

DCPG

N[C@H](C(O)=O)C1=CC=C(C(O)=O)C(=C1)C(O)=O

IJVMOGKBEVRBPP-ZETCQYMHSA-N

Agonist

GRM8

Yes

Yes

No

Yes