1. Chemogenomics
2. MTOR

MTOR

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

2475

3942

P42345

MTOR_HUMAN

Serine/threonine-protein kinase mTOR

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000602a

KU-0063794

OCC1=C(OC)C=CC(C2=CC=C3C(N=C(N4C[C@@H](C)O[C@@H](C)C4)N=C3N5CCOCC5)=N2)=C1

RFSMUFRPPYDYRD-CALCHBBNSA-N

MTOR

Yes

Yes

No

Yes

EUB0000607a

WYE-132

O=C(NC)NC(C=C1)=CC=C1C2=NC(N3CC4CCC(O4)C3)=C5C(N(C6CCC7(OCCO7)CC6)N=C5)=N2

QLHHRYZMBGPBJG-UHFFFAOYSA-N

MTOR

Yes

Yes

Yes

Yes

EUB0000676a

OSI-027

NC1=NC=NN2C1=C(C3=CC4=C(C(OC)=CC=C4)N3)N=C2[C@@H]5CC[C@@H](C(O)=O)CC5

JROFGZPOBKIAEW-HAQNSBGRSA-N

MTOR

Yes

Yes

No

Yes