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Chemogenomics
NUDT1

NUDT1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

4521

8048

P36639

8ODP_HUMAN

nudix hydrolase 1

Nudix hydrolase family

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000302b

BAY-707

CCNC(=O)c1cc2c(N3CCOC[C@H]3C)ccnc2[nH]1

RPMGXDCRCWWCRY-SNVBAGLBSA-N

NUDT1

No

Yes

No

Yes

EUB0000587a

BAY-604

CCNC(=O)c1cc2c(ccnc2n1C)N3CCOC[C@H]3C

SYYSMZCCSNLTHZ-LLVKDONJSA-N

Neg Ctrl (BAY-707)

NUDT1

Yes

No

Yes

The EUbOPEN project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 875510. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme, EFPIA companies and Associated Partners: KTH, OICR, Diamond and McGill. This communication reflects the views of the authors and neither IMI nor the European Union, EFPIA or any Associated Partners are liable for any use that may be made of the information contained herein.

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