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Chemogenomics
PRKCB

PRKCB

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

5579

9395

P05771

KPCB_HUMAN

Protein kinase C beta type

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000154b

Enzastaurin

Cn1cc(C2=C(c3cn(C4CCN(Cc5ccccn5)CC4)c4ccccc34)C(=O)NC2=O)c2ccccc21

AXRCEOKUDYDWLF-UHFFFAOYSA-N

PRKCA

PRKCB

PRKCE

PRKCG

Yes

EUB0000159b

Bisindolylmaleimide I

CN(C)CCCn1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)c2ccccc21

QMGUOJYZJKLOLH-UHFFFAOYSA-N

PRKCA

PRKCB

PRKCG

Yes

The EUbOPEN project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 875510. This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme, EFPIA companies and Associated Partners: KTH, OICR, Diamond and McGill. This communication reflects the views of the authors and neither IMI nor the European Union, EFPIA or any Associated Partners are liable for any use that may be made of the information contained herein.

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