1. Chemogenomics
2. SOS1

SOS1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

6654

11187

Q07889

SOS1_HUMAN

SOS Ras/Rac guanine nucleotide exchange factor 1

Guanine-nucleotide releasing factor

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000320b

BAY-293

CNCc1ccccc1-c1csc([C@@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1

WEGLOYDTDILXDA-OAHLLOKOSA-N

SOS1

Yes

Yes

No

Yes

EUB0000743a

BAY-294

CC1=NC(N[C@H](C2=CC(C3=CC=CC=C3CNC)=CS2)C)=C4C=C(OC)C(OC)=CC4=N1

WEGLOYDTDILXDA-HNNXBMFYSA-N

Neg Ctrl (BAY-293)

SOS1

No

Yes

Yes

Yes