1. Chemogenomics
2. CSF1R

CSF1R

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

1436

2433

P07333

CSF1R_HUMAN

Macrophage colony-stimulating factor 1 receptor

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000598a

GW 2580

NC1=NC(N)=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=N1

MYQAUKPBNJWPIE-UHFFFAOYSA-N

CSF1R

Yes

Yes

No

Yes

EUB0000660aPO4

Motesanib

O=C(NC1=CC=C(C(C)(C)CN2)C2=C1)C3=C(NCC4=CC=NC=C4)N=CC=C3.OP(O)(O)=O.OP(O)(O)=O

ONDPWWDPQDCQNJ-UHFFFAOYSA-N

CSF1R

,

FLT1

,

FLT4

,

KDR

,

KIT

,

PDGFRA

,

PDGFRB

,

RET

,

ZAP70

Yes

Yes

No

Yes

EUB0000697a

PLX5622

CC1=CN=C(NC=C2CC3=C(F)N=C(NCC4=C(OC)N=CC(F)=C4)C=C3)C2=C1

NSMOZFXKTHCPTQ-UHFFFAOYSA-N

CSF1R

No

Yes

No

Yes