ERBB2
Compound EUbOPEN ID
Compound name
Compound image
SMILES / InChIKey
Mode of action
Main target
Chem QC data available
Incucyte cytotox data available
Multiplex data available
Other annotation data available
EUB0000592a
Neratinib
CN(C/C=C/C(NC1=CC(C(NC2=CC(Cl)=C(OCC3=NC=CC=C3)C=C2)=C(C#N)C=N4)=C4C=C1OCC)=O)C
JWNPDZNEKVCWMY-VQHVLOKHSA-N
Yes
EUB0000595a
CP724714
CC1=CC(NC2=NC=NC3=CC=C(/C=C/CNC(COC)=O)C=C32)=CC=C1OC4=CC=C(C)N=C4
LLVZBTWPGQVVLW-SNAWJCMRSA-N
Yes
EUB0000596aBDA
Afatinib (dimaleate)
CN(C/C=C/C(=O)NC1=C(C=C2N=CN=C(C2=C1)NC3=CC(=C(C=C3)F)Cl)O[C@@H]4COCC4)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O
USNRYVNRPYXCSP-JUGPPOIOSA-N
No
EUB0000600aCl
Canertinib (dihydrochloride)
C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4.Cl.Cl
JZZFDCXSFTVOJY-UHFFFAOYSA-N
No
EUB0000616aPTSA
AST-1306 (tosylate)
CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
ZMUKJEHWLJBODV-UHFFFAOYSA-N
Yes
EUB0000654a
HKI 357
O=C(/C=C/CN(C)C)NC1=C(OCC)C=C(N=CC(C#N)=C2NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)C2=C1
NERXPXBELDBEPZ-RMKNXTFCSA-N
No
