1. Chemogenomics
  2. MAP2K2

MAP2K2

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family
5605
6842
P36507
MP2K2_HUMAN
Dual specificity mitogen-activated protein kinase kinase 2
Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available
EUB0000129b
Selumetinib
Chemical structure of compound Selumetinib
CN(C=N1)C2=C1C(F)=C(NC3=CC=C(Br)C=C3Cl)C(C(NOCCO)=O)=C2
CYOHGALHFOKKQC-UHFFFAOYSA-N
MAP2K1
,
MAP2K2
Yes
Yes
No
Yes
EUB0000599a
CI-1040
Chemical structure of compound CI-1040
C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
GFMMXOIFOQCCGU-UHFFFAOYSA-N
MAP2K1
,
MAP2K2
Yes
Yes
No
Yes
EUB0000666a
PD0325901
Chemical structure of compound PD0325901
FC1=C(F)C(NC2=CC=C(I)C=C2F)=C(C(NOC[C@H](O)CO)=O)C=C1
SUDAHWBOROXANE-SECBINFHSA-N
MAP2K1
,
MAP2K2
Yes
Yes
No
Yes