1. Chemogenomics
2. OPRL1

OPRL1

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

4987

8155

P41146

OPRX_HUMAN

opioid related nociceptin receptor 1

GPCR

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000427aCl

JTC-801

CCC1=CC=C(OCC2=CC=CC=C2C(=O)NC2=CC3=C(N)C=C(C)N=C3C=C2)C=C1

NQLIYKXNAXKMBL-UHFFFAOYSA-N

Antagonist

OPRL1

,

OPRM1

Yes

Yes

Yes

Yes

EUB0000468a

SCH 221510

CC1=CC=CC=C1C(N1C2CCC1CC(O)(C2)C1=CC=CC=C1)C1=C(C)C=CC=C1

LOSJNRBXNQTUNT-UHFFFAOYSA-N

Agonist

OPRL1

Yes

Yes

Yes

Yes