1. Chemogenomics
2. TYRO3

TYRO3

NCBI gene ID HGNC ID UniProt ID SwissProt ID Description Protein family

7301

12446

Q06418

TYRO3_HUMAN

Tyrosine-protein kinase receptor TYRO3

Protein Kinase

Compounds

Compound EUbOPEN ID Compound name Compound image SMILES / InChIKey Mode of action Main target Chem QC data available Incucyte cytotox data available Multiplex data available Other annotation data available

EUB0000147b

LDC1267

CCOc1cn(-c2ccc(F)cc2C)nc1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1

ISPBCAXOSOLFME-UHFFFAOYSA-N

AXL

,

MERTK

,

TYRO3

Yes

Yes

No

No

EUB0000624a

BMS 777607

CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F

VNBRGSXVFBYQNN-UHFFFAOYSA-N

AXL

,

MET

,

MST1R

,

TYRO3

Yes

Yes

No

No